Endotoxin and Pyrogen Testing Products
The next chapter in endotoxin testing... Let's write it together.
The next chapter in endotoxin testing... Let's write it together.
Make the right choices in drug discovery...Together we can develop your next biological model.
Together, these enable our customers to deliver their discoveries. We are a preferred global partner to the pharmaceutical, biotech and specialty ingredients markets. Our solutions improve life quality by preventing illness, enabling healthier lifestyles and supporting a safe environment.
Testing for pyrogens is a critical step in ensuring parenteral pharmaceutical product and medical device safety. The monocyte activation test (MAT) can detect both endotoxin and non-endotoxin pyrogens in one in vitro test.
Used to detect both endotoxins and non-endotoxin pyrogens in parenteral products, such as pharmaceuticals and medical devices.Samples are incubated in human monocytes which produce cytokines/interleukins (IL) if pyrogens are present, these cytokines/interleukins are detected in an immunological assay (ELISA).
The Limulus Amebocyte Lysate (LAL) assay has widely replaced Rabbit Pyrogen Test as a much more sensitive and specific bacterial endotoxin test for pharmaceutical and biotechnology products
Used to detect endotoxins in parenteral products, such as pharmaceuticals and medical devices. Available as Gel Clot LAL Assays, Chromogenic LAL Assays & Turbidimetric LAL Assays.
Developed as an animal-free alternative to the BET test
PyroGeneTM rFC Assay does not use horseshoe crab blood as the raw material, therefore, there is less dependence on the animal, which results in less animal utilization and offers an animal-free security of supply.
the next endotoxin advance… Let’s automate it together.
For decades, you have relied on us for our endotoxin testing products, services and software to meet the ever-changing needs of regulated manufacturing environments.
WinKQCL® Endotoxin Detection & Analysis Software.
As experts in digital control systems, we have always embraced data integrity by providing quantitative endotoxin detection systems that are easy to use and help ensure reliable, reproducible, and accurate electronic results in accordance with the strictest regulatory standards.
Our portfolio of integrated solutions for drug discovery can serve as a key foundation for developing the right biological model systems. Our broad choice of primary cells and optimized cell culture systems provides the backbone to build cellular models with consistent assay performance.
Our products and services are optimized to work with each other to guarantee consistent and reproducible results in biologically relevant models such as in vitro assay systems in human primary cells.
Our broad choice of primary cells and optimized cell culture systems and reagents provides the backbone to build cellular models with consistent assay performance.
Our products and services are optimized to work with each other to guarantee consistent and reproducible results in biologically relevant models such as in vitro assay systems in human primary cells.
Our broad choice of primary cells and optimized cell culture systems and reagents provides the backbone to build cellular models with consistent assay performance.
Cell and gene therapies are combined in some techniques, such as ex vivo chimeric antigen receptor (CAR) T-cell therapy. But they can also be utilized entirely independently, for example, in mesenchymal stem cell (MSC) therapy (cell therapy only) and in vivo viral gene transfection (gene therapy only).
We offer Primary cells, Stem cells and media to support both human and animal cell models
Have access to the right type of culture media for your specific cell type and application. Various types of reagents and buffers are required to maintain cell cultures, including amino acids, antibiotics and growth factors.
Understanding the absorption, distribution, metabolism, excretion (ADME), and toxicity (ADME-Tox) of new drugs is a key element of drug discovery. These studies provide insights into the disposition of a pharmaceutical compound in the body, including its safety and efficacy.
Lonza offers a wide range of cryopreserved hepatocytes cells, media and microsomes. We have three different highly sensitive assays that have been developed to safely and quickly assess the health ofyour 2D and 3D cell cultures.
Helping you find solutions for your research wether it is to increase effciciency, agility , productivity and sustainability. Access application resources for more success as you plan and execute your experiments.